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mmp 9  (R&D Systems)


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    R&D Systems mmp 9
    Mmp 9, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mmp+8/pmc12916252-107-59-61?v=R%26D+Systems
    Average 94 stars, based on 2 article reviews
    mmp 9 - by Bioz Stars, 2026-08
    94/100 stars

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    Identification of Micheliolide, a potential MMP8 regulator. A , qRT-PCR analysis of MMP8 expression in capsular tissues 24 hours after ECLE surgery, combined with anterior chamber injection of saline or MCL, n = 3, N = 18. B , Western blot analysis and quantification of MMP8 protein levels in capsular tissues 24 hours after ECLE surgery with anterior chamber injection of saline or MCL, n = 4, N = 20. C , qRT-PCR analysis of MMP8 expression in LECs pretreated with or without 5 μmol/L MCL and stimulated with 10 ng/mL TGF-β2 for 48 hours, n = 6. D , Western blot and corresponding quantification of MMP8 protein expression in LECs pretreated with or without 5 μmol/L MCL followed by stimulation with 10 ng/mL TGF-β2 for 48 hours, n = 4. E , Molecular docking simulation of Micheliolide and MCL, with the interacting MMP8 amino acids represented by blue sticks. F , CETSA was used to assess the thermal instability of the interaction between MMP8 and MCL over the temperature range of 58 °C to 78 °C, n = 4

    Journal: Journal of Translational Medicine

    Article Title: Micheliolide suppresses epithelial-mesenchymal transition of lens epithelial cells via downregulating matrix metalloproteinase 8 to ameliorate posterior capsular opacification

    doi: 10.1186/s12967-026-07890-z

    Figure Lengend Snippet: Identification of Micheliolide, a potential MMP8 regulator. A , qRT-PCR analysis of MMP8 expression in capsular tissues 24 hours after ECLE surgery, combined with anterior chamber injection of saline or MCL, n = 3, N = 18. B , Western blot analysis and quantification of MMP8 protein levels in capsular tissues 24 hours after ECLE surgery with anterior chamber injection of saline or MCL, n = 4, N = 20. C , qRT-PCR analysis of MMP8 expression in LECs pretreated with or without 5 μmol/L MCL and stimulated with 10 ng/mL TGF-β2 for 48 hours, n = 6. D , Western blot and corresponding quantification of MMP8 protein expression in LECs pretreated with or without 5 μmol/L MCL followed by stimulation with 10 ng/mL TGF-β2 for 48 hours, n = 4. E , Molecular docking simulation of Micheliolide and MCL, with the interacting MMP8 amino acids represented by blue sticks. F , CETSA was used to assess the thermal instability of the interaction between MMP8 and MCL over the temperature range of 58 °C to 78 °C, n = 4

    Article Snippet: To explore the role of Matrix Metalloproteinase 8 (MMP8) in the effect of MCL on EMT, a MMP8 inhibitor (Cat. HY-N1454, MedChemExpress, State of New Jersey, USA), referred to as M8I, was used in the present study.

    Techniques: Quantitative RT-PCR, Expressing, Injection, Saline, Western Blot

    MCL inhibits EMT by regulating MMP8 expression. A , Viability of LECs treated with a gradient concentration of M8I, n = 8. B , Western blot analysis of EMT-related markers in LECs induced by TGF-β2 and treated with MCL alone or in combination with M8I, n = 4. C , Quantitative analysis of the Western blot results shown in ( B ), normalized to GAPDH. D , Coimmunofluorescence staining for αSMA (red) and MMP8 (green) in LECs induced by TGFβ2 and treated with MCL alone or in combination with M8I, n = 3, scale bar = 100um. E , Quantification of immunofluorescence intensity

    Journal: Journal of Translational Medicine

    Article Title: Micheliolide suppresses epithelial-mesenchymal transition of lens epithelial cells via downregulating matrix metalloproteinase 8 to ameliorate posterior capsular opacification

    doi: 10.1186/s12967-026-07890-z

    Figure Lengend Snippet: MCL inhibits EMT by regulating MMP8 expression. A , Viability of LECs treated with a gradient concentration of M8I, n = 8. B , Western blot analysis of EMT-related markers in LECs induced by TGF-β2 and treated with MCL alone or in combination with M8I, n = 4. C , Quantitative analysis of the Western blot results shown in ( B ), normalized to GAPDH. D , Coimmunofluorescence staining for αSMA (red) and MMP8 (green) in LECs induced by TGFβ2 and treated with MCL alone or in combination with M8I, n = 3, scale bar = 100um. E , Quantification of immunofluorescence intensity

    Article Snippet: To explore the role of Matrix Metalloproteinase 8 (MMP8) in the effect of MCL on EMT, a MMP8 inhibitor (Cat. HY-N1454, MedChemExpress, State of New Jersey, USA), referred to as M8I, was used in the present study.

    Techniques: Expressing, Concentration Assay, Western Blot, Staining, Immunofluorescence

    MCL ameliorates the inflammatory response and suppresses the proliferation, migration, and EMT of LECs following cataract surgery via targeting MMP8. PCS, post-cataract surgery

    Journal: Journal of Translational Medicine

    Article Title: Micheliolide suppresses epithelial-mesenchymal transition of lens epithelial cells via downregulating matrix metalloproteinase 8 to ameliorate posterior capsular opacification

    doi: 10.1186/s12967-026-07890-z

    Figure Lengend Snippet: MCL ameliorates the inflammatory response and suppresses the proliferation, migration, and EMT of LECs following cataract surgery via targeting MMP8. PCS, post-cataract surgery

    Article Snippet: To explore the role of Matrix Metalloproteinase 8 (MMP8) in the effect of MCL on EMT, a MMP8 inhibitor (Cat. HY-N1454, MedChemExpress, State of New Jersey, USA), referred to as M8I, was used in the present study.

    Techniques: Migration